Vitamin B Profile
Private Vitamin B Profile testing in London for £616, measuring 6 key B-vitamin markers with specialist results expected in around 5 days.
Turnaround time
5 business days
Biomarkers count
6
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Overview of the Vitamin B Profile Test
The Vitamin B Profile measures 6 B-vitamin biomarkers involved in cellular energy metabolism, neurological function, DNA synthesis and healthy red blood cell production.
The profile includes Active B12, Vitamin B1 (Thiamine), Vitamin B2, Vitamin B3, Vitamin B6 (pyridoxine) and Red Cell Folate.
B vitamins are water-soluble micronutrients that work together across numerous metabolic pathways.
Vitamin B1 is essential for carbohydrate metabolism and normal nerve and cardiac function.
Vitamin B2 contributes to energy-producing oxidation-reduction reactions and supports normal cellular metabolism.
Vitamin B3 is a precursor for NAD and NADP, coenzymes required for hundreds of metabolic reactions.
Vitamin B6 contributes to amino-acid metabolism, neurotransmitter synthesis and haemoglobin production.
Red Cell Folate provides information about longer-term Vitamin B9 status and is important for DNA synthesis and normal blood-cell formation.
Active B12 measures holotranscobalamin, the fraction of circulating Vitamin B12 that is available for uptake by cells.
Combined assessment can be particularly useful when symptoms are non-specific or several deficiencies may coexist.
Risk factors include restrictive diets, malabsorption, gastrointestinal surgery, alcohol excess and selected medicines.
High supplementation can also produce elevated results.
Vitamin B6 is especially important in this respect because excessive long-term intake can itself cause peripheral neuropathy.
The profile should therefore guide targeted nutritional correction rather than indiscriminate B-complex supplementation.
What Does the Vitamin B Profile Test Check?
The profile measures six B-vitamin biomarkers involved in metabolism, neurological health and blood-cell production. This test measures 6 biomarkers.
Active B12
Measures biologically available Vitamin B12 that is bound to holotranscobalamin and accessible to cells.
Vitamin B1 (Thiamine)
Measures Thiamine, essential for energy metabolism and normal nerve function.
Vitamin B2
Measures Riboflavin status, supporting assessment of cellular energy and redox metabolism.
Vitamin B3
Measures Vitamin B3 status, relevant to NAD and NADP-dependent metabolic processes.
Vitamin B6 (pyridoxine)
Measures Vitamin B6, required for amino-acid metabolism, neurotransmitter production and haemoglobin synthesis.
Red Cell Folate
Measures Folate stored within red blood cells, providing information about longer-term Vitamin B9 status.
Who May Benefit From the Vitamin B Profile Test?
The profile can be useful where several B-vitamin abnormalities are possible.
People with persistent fatigue or low energy - Several B vitamins participate in energy-producing pathways.
People with tingling, numbness or neurological symptoms - B1, B6, Folate and B12 can all affect nervous-system function.
Vegans or people with very limited animal-product intake - Vitamin B12 deficiency risk can be increased.
People with gastrointestinal malabsorption - Coeliac disease, inflammatory bowel disease and surgery can affect vitamin absorption.
People with macrocytosis or anaemia - Folate and B12 abnormalities can affect red-blood-cell production.
People taking Metformin or long-term acid-suppressing medication - These medicines can contribute to reduced B12 status in some people.
People taking high-dose B-complex supplements - Testing can identify excessive as well as deficient concentrations.
People with previous multiple B-vitamin abnormalities - A profile can provide a broader follow-up assessment.
How to Prepare
Do not stop medically prescribed B12 or Folate treatment solely to alter the blood result.
Supplement use is important to interpretation and should be recorded accurately.
Symptoms and Reasons to Consider the Vitamin B Profile Test
B-vitamin abnormalities can affect energy, blood-cell production and the nervous system.
Persistent fatigue - Deficiencies affecting energy metabolism or anaemia can contribute to tiredness.
Tingling or numbness - B12 and other B-vitamin abnormalities can affect peripheral nerves.
Brain fog or poor concentration - Nutritional deficiency is one possible contributor.
Macrocytosis or unexplained anaemia - Folate and B12 are particularly relevant.
A sore or inflamed tongue - This can occur with several nutritional deficiencies.
Restricted diet or malabsorption - These increase the risk of combined deficiencies.
Long-term supplement use - Excessive Vitamin B6 can itself cause neurological symptoms.
Neurological symptoms should not automatically be attributed to vitamin deficiency.
Significant or progressive numbness, weakness or cognitive change requires appropriate clinical assessment.
How to Book Your Vitamin B Profile Test
The Vitamin B Profile can be booked privately for comprehensive B-vitamin assessment.
Choose the Vitamin B Profile
Select the 6-marker Vitamin B Profile online.
Select your sample collection option
Choose an in-clinic blood draw or professional home or hotel phlebotomy where suitable.
Attend your appointment
A trained healthcare professional collects the required blood specimens using the appropriate laboratory tubes.
Laboratory analysis
Your samples undergo measurement of Active B12, Vitamin B1, Vitamin B2, Vitamin B3, Vitamin B6 and Red Cell Folate.
Receive your results securely
Your authorised results are delivered securely and can be interpreted individually and as part of your wider nutritional assessment.
When Will I Receive My Results?
The current live London Blood Tests page lists a turnaround of approximately 5 days after laboratory receipt for the Vitamin B Profile.
Several specialist vitamin assays are processed together within this panel.
The complete profile follows the turnaround of the slowest included marker.
Understanding Your Results
Each B-vitamin result is interpreted separately.
A low result can reflect inadequate intake, impaired absorption, medication effects or increased physiological need.
B12 and Folate results deserve particular attention when macrocytosis or anaemia is present.
Low Active B12 can identify reduced cellularly available B12 even when Total B12 is less clearly abnormal.
A high result frequently reflects supplementation.
High Vitamin B6 is clinically relevant because excessive long-term exposure can cause sensory neuropathy.
The profile should therefore be used to identify exactly which nutrients require correction.
Supplementing all B vitamins at high doses without evidence of deficiency is not necessarily appropriate.
Why Book With London Blood Tests?
London Blood Tests provides private multi-marker B-vitamin testing for detailed nutritional assessment.
Measures 6 B-vitamin biomarkers - The profile covers several complementary metabolic pathways.
Includes Active B12 - This measures the fraction of B12 available for cellular uptake.
Includes Red Cell Folate - Red-cell measurement provides information about longer-term Folate status.
Relevant to neurological symptoms - Several included vitamins support normal nerve function.
Relevant to anaemia assessment - B12 and Folate are essential for normal red-blood-cell production.
Specialist laboratory analysis - Multiple individual vitamin assays are processed within one profile.
Professional blood collection - Clinic and suitable home or hotel collection are available.
Clear pricing - The Vitamin B Profile costs £616.
Private Vitamin B Profile Blood Test in London
London Blood Tests provides private Vitamin B Profile testing for people requiring a broad assessment of B-vitamin status.
The profile costs £616 and measures 6 B-vitamin biomarkers.
Results are expected approximately 5 days after laboratory receipt.
The profile can identify both deficiencies and potentially excessive supplementation.