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VLDL Cholesterol

Organ Function & Health
145.70

The VLDL cholesterol blood test measures very low-density lipoprotein levels linked to triglycerides. It helps assess cardiovascular and metabolic risk.

Turnaround time

8 days

Biomarkers count

1

Same-Day Appointments
UKAS Accredited Labs

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Under 18? Patients under 18 can only be seen at GB Medlabs and Clinilabs, Monday to Friday only.
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Details about VLDL Cholesterol

What is the VLDL Cholesterol test?

The VLDL (Very Low-Density Lipoprotein) cholesterol test measures the amount of VLDL particles in the blood. VLDL is produced by the liver and primarily carries triglycerides to tissues, making it closely linked to fat metabolism.

Unlike LDL cholesterol, VLDL is not usually measured directly but calculated from triglyceride levels in standard lipid testing. Elevated VLDL is associated with increased cardiovascular risk and metabolic conditions.

Clinically, this test is used as part of lipid and heart health assessment, especially when triglycerides are elevated or metabolic syndrome is suspected.

 

Why do I need a test for VLDL Cholesterol?

High VLDL cholesterol levels indicate excess circulating triglycerides, which can contribute to plaque formation in arteries. This increases the risk of heart disease, stroke, and other cardiovascular complications.

VLDL testing is particularly important for individuals with obesity, diabetes, insulin resistance, or a family history of cardiovascular disease. It also helps guide lifestyle and dietary interventions.

You may benefit from a VLDL test if you experience or have:

  • High triglyceride levels
  • Type 2 diabetes or insulin resistance
  • Obesity or central weight gain
  • High-fat diet or excessive alcohol intake
  • Family history of heart disease
  • Metabolic syndrome

 

Benefits of the VLDL Cholesterol test

  1. Assesses triglyceride-related risk
    Provides insight into lipid transport and fat metabolism.
  2. Supports cardiovascular risk evaluation
    Elevated VLDL is linked to atherosclerosis.
  3. Complements standard lipid testing
    Adds context beyond total and LDL cholesterol.
  4. Identifies metabolic imbalance
    Useful in insulin resistance and metabolic syndrome.
  5. Guides lifestyle modification
    Helps tailor diet and exercise recommendations.
  6. Supports diabetes risk assessment
    Elevated VLDL often accompanies poor glucose control.
  7. Monitors response to treatment
    Tracks improvement after dietary or medical intervention.
  8. Improves preventive care decisions
    Helps identify risk before clinical disease develops.

 

Step-by-step – How we offer this test

Option 1: Clinic-based blood test (UK-wide)

  • Choose your nearest UK clinic
  • Attend your appointment
  • A clinician draws a blood sample
  • Results are analysed and reported

Option 2: Home or hotel visit (UK-wide)

  • A qualified phlebotomist comes to your location
  • Blood sample taken in your home or hotel
  • No need to travel
  • Same laboratory processing and reporting

 

Your results explained

Low VLDL Cholesterol levels

Low VLDL levels generally indicate low triglyceride transport and are not usually a cause for concern.

UK reference range (low):

  • < 0.1 mmol/L

Low levels are typically associated with healthy lipid metabolism.

 

Normal VLDL Cholesterol levels

Normal levels suggest balanced triglyceride transport and lower cardiovascular risk.

UK reference range (normal):

  • 0.1 – 0.5 mmol/L

Within this range, VLDL-related risk is considered low.

 

High VLDL Cholesterol levels

High VLDL levels indicate elevated triglycerides and increased cardiovascular and metabolic risk.

UK reference range (high):

  • > 0.5 mmol/L

High levels are associated with obesity, diabetes, excess alcohol intake, and fatty liver disease.

How It Works

Simple steps to get your results

1

Book Online

Choose your test online and book in seconds. Select your preferred clinic location or home visit option.

2

Visit or Test at Home

Attend one of our UK or London clinics, arrange a home nurse visit, or use a finger-prick kit where available.

3

Get Your Results

Your sample is analysed by accredited UK laboratories, with secure results delivered directly to you.

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How to Prepare for Your Test

Follow these guidelines for accurate results

Sample Timing

Where possible, attend your blood test between 7am and 12pm. Please wait until any short-term illness or infection has fully resolved before testing. Avoid intense exercise for 24–48 hours beforehand, as this can affect certain markers.

Fasting & Hydration

Fasting is not always required, but some tests may recommend it. If fasting is advised, avoid food for 8–12 hours before your appointment and drink water only. Stay well hydrated, as this helps with sample collection and accuracy.

Medications & Supplements

Continue prescribed medications unless advised otherwise by your clinician. Avoid vitamin, mineral, or biotin supplements for at least 24–48 hours before your test, as these can interfere with results. If you are unsure about any medication or supplement, please let us know before your appointment.

Hormones & Menstrual Cycle

For hormone-related tests, timing within your menstrual cycle may be important. If relevant, follow any specific guidance provided on your test page.

If you have any questions or special circumstances, our team is happy to advise before your appointment.

Frequently Asked Questions

It measures very low-density lipoprotein cholesterol, which carries triglycerides in the blood.

They are closely related, but VLDL represents the transport particles that carry triglycerides.

Yes, fasting for 9–12 hours is usually recommended for accurate triglyceride-related results.

Yes. High sugar, refined carbohydrates, alcohol, and excess calories can raise VLDL levels.

Yes. Elevated VLDL increases the risk of heart disease and stroke.

Regular physical activity can significantly reduce triglycerides and VLDL levels.

It is usually calculated rather than directly measured.

Yes. Statins, fibrates, and omega-3 fatty acids may reduce VLDL.

Yes. High VLDL is commonly seen in insulin resistance and diabetes.

Usually annually, or more frequently if managing lipid disorders.

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